Sahoo S.; Pal S.2025-02-17202125http://dx.doi.org/10.1021/acs.joc.0c02926https://idr.iitbbs.ac.in/handle/2008/3530An efficient and atom-economical palladium-catalyzed intramolecular cross dehydrogenative coupling (CDC) reaction has been developed for the construction of highly ?-conjugated benzimidazo[1,2-a]quinoline-fused isoxazole scaffolds using molecular oxygen as sole oxidant. The approach portrayed wide substrate scope with good functional group tolerance and depicted a useful tool for the generation of fluorescence active compounds with high quantum yield. Synthetic versatility of the method via Fe-catalyzed reductive isoxazole ring cleavage toward pyridine, pyrimidine, pyrazole fused heteropolycyclic compounds has been showcase. � 2021 American Chemical Society.enArticle