Palladium(II) in electrophilic activation of aldehydes and enones: Efficient C-3 functionalization of indoles
| dc.contributor.author | Mohapatra S.S. | en_US |
| dc.contributor.author | Mukhi P. | en_US |
| dc.contributor.author | Mohanty A. | en_US |
| dc.contributor.author | Pal S. | en_US |
| dc.contributor.author | Sahoo A.O. | en_US |
| dc.contributor.author | Das D. | en_US |
| dc.contributor.author | Roy S. | en_US |
| dc.date.accessioned | 2025-02-17T05:20:25Z | |
| dc.date.issued | 2015 | |
| dc.description.abstract | The regioselective C-3 alkylation of indoles with aldehydes and enones as electrophiles is catalyzed by a d8 late transition metal complex PdCl<inf>2</inf>(MeCN)<inf>2</inf> at room temperature in the presence of air/moisture and in the absence of any additional acid/base, additive, or ligand. The active catalyst in this alkylation is an organometallic intermediate C1 which is formed from the reaction of indole with the palladium(II) pre-catalyst. The crystallographic characterization and reactivity of C1 and its analogs with indoles and surrogates is in progress. � 2015 Elsevier Ltd. All rights reserved. | en_US |
| dc.identifier.citation | 6 | en_US |
| dc.identifier.uri | http://dx.doi.org/10.1016/j.tetlet.2015.08.080 | |
| dc.identifier.uri | https://idr.iitbbs.ac.in/handle/2008/698 | |
| dc.language.iso | en | en_US |
| dc.subject | Alkylation | en_US |
| dc.subject | C-C bond formation | en_US |
| dc.subject | Carbonyl | en_US |
| dc.subject | Catalysis | en_US |
| dc.subject | Indole | en_US |
| dc.subject | Palladium | en_US |
| dc.title | Palladium(II) in electrophilic activation of aldehydes and enones: Efficient C-3 functionalization of indoles | en_US |
| dc.type | Article | en_US |