IDR Logo

Please use this identifier to cite or link to this item: http://idr.iitbbs.ac.in/jspui/handle/2008/856
Title: Influence of boron addition to Ti-13Zr-13Nb alloy on MG63 osteoblast cell viability and protein adsorption
Authors: Majumdar P.
Singh S.B.
Dhara S.
Chakraborty M.
Keywords: Boron
MTT assay
Protein adsorption
Titanium alloy
Issue Date: 2015
Citation: 10
Abstract: Cell proliferation, cell morphology and protein adsorption on near ?-type Ti-13Zr-13Nb (TZN) alloy and Ti- 13Zr-13Nb-0.5B (TZNB) composite have been investigated and compared to evaluate the effect of boron addition which has been added to the Ti alloy to improve their poor tribological properties by forming in situ TiB precipitates. MG63 cell proliferation on substrateswith different chemistry but the same topography was compared. TheMTT assay test showed that the cell viability on the TZN alloy was higher than the boron containing TZNB composite after 36 h of incubation and the difference was pronounced after 7 days. However, both the materials showed substantially higher cell attachment than the control (polystyrene). For the same period of incubation in fetal bovine serum(FBS), the amount of protein adsorbed on the surface of boron free TZN sampleswas higher than that in the case of boron containing TZNB composite. The presence of boron in the TZN alloy influenced protein adsorption and cell response and they are lower in TZNB than in TZNas a result of the associated difference in chemical characteristics. � 2014 Elsevier B.V. All rights reserved.
URI: http://dx.doi.org/10.1016/j.msec.2014.10.012
http://10.10.32.48:8080/jspui/handle/2008/856
Appears in Collections:Research Publications

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.