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Please use this identifier to cite or link to this item: http://idr.iitbbs.ac.in/jspui/handle/2008/1474
Title: Mercury based drug in ancient India: The red sulfide of mercury in nanoscale
Authors: Mukhi P.
Mohapatra S.S.
Bhattacharjee M.
Ray K.K.
Muraleedharan T.S.
Arun A.
Sathyavathi R.
Juluri R.R.
Satyam P.V.
Panda A.K.
Biswas A.
Nayak S.
Bojja S.
Pratihar S.
Roy S.
Keywords: Mercury sulfide
Nanoparticle
Radical scavenging
Rasasindur
Issue Date: 2017
Citation: 4
Abstract: Mercury is one of the elements which had attracted the attention of the chemists and physicians of ancient India and China. Among the various metal based drugs which utilize mercury, we became interested in the red sulfide of mercury which is known in ancient Indian literature as rasasindur (alias rasasindura, rasasindoor, rasasinduram, sindur, or sindoor) and is used extensively in various ailments and diseases. Following various physico-chemical characterizations it is concluded that rasasindur is chemically pure ?-HgS with Hg:S ratio as 1:1. Analysis of rasasindur vide Transmission Electron Microscopy (TEM) showed that the particles are in nanoscale. Bio-chemical studies of rasasindur were also demonstrated. It interacts with Bovine Serum Albumin (BSA) with an association constant of (9.76 � 0.56) � 103 M?1 and behaves as a protease inhibitor by inhibiting the proteolysis of BSA by trypsin. It also showed mild antioxidant properties. � 2017 Transdisciplinary University, Bangalore and World Ayurveda Foundation
URI: http://dx.doi.org/10.1016/j.jaim.2017.01.009
http://10.10.32.48:8080/jspui/handle/2008/1474
Appears in Collections:Research Publications

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